Dr. Kaye was born in New Jersey but grew up in different parts of the South. He received his undergraduate degree in biology from the University of North Carolina at Chapel Hill in 2004 and obtained his doctorate in veterinary medicine from the University of Georgia in 2008. After a one year rotating internship in small animal medicine and surgery at Tufts University, he returned to the University of Georgia to complete a residency in medical oncology from 2009-2012. Dr. Kaye became board-certified in oncology by the American College of Veterinary Internal Medicine in 2013.

Dr. Kaye has performed research on bladder cancer in dogs, although he finds all aspects of canine and feline oncology to be rewarding. He joined Massachusetts Veterinary Referral Hospital in September 2012.